From Concept to Commissioning
Room data, heat-load design, air distribution and pressure control developed for API pharmaceutical production.
From User Requirement Specifications (URS), heat load modeling, and SMACNA duct layouts to chilled/hot water piping, MCC panels, and ISO 14644-3 validation testing.
| ROOM NAME | CLEANLINESS CLASS | AREA | TEMPERATURE | RELATIVE HUMIDITY | DIFF. PRESSURE | ACPH | SUPPLY CFM |
|---|---|---|---|---|---|---|---|
| Crystallization & Filtration | ISO Class 8 (Grade D) | 45 m² | 22 ± 2°C | 50 ± 5% | +30 Pa | 22 ACPH | 2,400 CFM |
| Powder Milling & Sifting | ISO Class 8 (Grade D) | 35 m² | 21 ± 2°C | 45 ± 5% | +30 Pa | 25 ACPH | 2,200 CFM |
| Blender & Final Packing | ISO Class 8 with LAF (Grade A) | 50 m² | 20 ± 2°C | 40 ± 5% | +35 Pa | 28 ACPH | 3,500 CFM |
| Personnel Airlock (PAL) | ISO Class 8 (Grade D) | 12 m² | 23 ± 2°C | < 60% | +15 Pa | 20 ACPH | 600 CFM |
| Material Airlock (MAL) | ISO Class 8 (Grade D) | 16 m² | 23 ± 2°C | < 60% | +15 Pa | 20 ACPH | 800 CFM |
Calculation of sensible and latent heat loads, occupant air changes, fresh air intake percentages, and system zoning to size AHUs with zero wasted cooling tons.
Engineering water chillers, cooling towers, primary/secondary circulation pumps, and hot water recirculation loops with exact pipe sizing and insulation BOQs.
Witnessing filter integrity (PAO aerosol leak testing), air velocity profiling, room differential pressure logging, and recovery tests to issue operational clearance.